This is part of its efforts to popularize science to the General Public and Students who are pursuing science as their career. TNSF attempt to focus on students on higher science as everyone knows
that learning of science at college within the curriculum is not enough to acquire holistic knowledge of science at the appropriate time. Hence, to fill the gap between what students are acquiring through the curriculum and what
it is required, TNSF is planning its activities on higher science to students who are pursuing higher education.
The 2020 Nobel Prize in Physiology or Medicine is awarded to Harvey J. Alter, Michael Houghton and Charles M. Rice for the discovery of Hepatitis C virus. Hepatitis, from the Greek names for liver and inflammation, is a disease characterized by poor appetite, vomiting, fatigue and jaundice – yellow discoloration of the skin and eyes. Chronic hepatitis leads to liver damage, which may progress to cirrhosis and liver cancer. Viral infection is the leading cause of hepatitis, with some forms persisting without symptoms for many years before life-threatening complications develop. Until the 1960’s, exposure to blood from infected individuals was a major health hazard, with up to 30% risk of chronic hepatitis following surgery or multiple blood transfusions. This risk was only partially reduced by the discovery of the Hepatitis B virus (HBV) and the eventual elimination of HBV-contaminated blood through testing. A more insidious form of hepatitis, characterized by very mild symptoms in the acute phase and a high risk of progression to chronic liver damage and cancer, remained. The work of Alter, Houghton and Rice characterized this form of hepatitis to be a distinct clinical entity, caused by an RNA virus of the Flavivirus family, now known as Hepatitis C virus (HCV). This pioneering work has paved the way for the development of screening methods that have dramatically reduced the risk of acquiring hepatitis from contaminated blood and has led to the development of effective antiviral drugs that have improved the lives of millions of people.
Introduction
Dr. Shahid Jameel
Director, Trivedi School of Biosciences, Ashoka University
The discovery of Hepatitis 'C' virus
Question & Answer
Dr. Shahid Jameel studied Chemistry at the Aligarh Muslim University and Indian Institute of Technology-Kanpur, India and obtained a PhD in Biochemistry at Washington State University, USA. His postdoctoral work was in Molecular Virology at the University of Colorado Health Sciences Center, Denver, USA. In 1988 Dr. Jameel set up the Virology Group at the International Centre for Genetic Engineering and Biotechnology, New Delhi, India and led it for 25 years, where his research focused on human viruses. In 2013 he was appointed as CEO of the DBT/Wellcome Trust India Alliance, a biomedical research charity based in India. He is a Fellow of the Indian Academy of Sciences as also the Indian National Science Academy and the national Academy of Sciences. Currently Dr Jameel is Director, Trivedi School of Biosciences at Ashoka University, Sonepat, Haryana.