This is part of its efforts to popularize science to the general public and students who are pursuing science as their career. TNSF attempt to focus on students on higher science as everyone knows that learning of science at college within the curriculum is not enough to acquire holistic knowledge of science at the appropriate time. Hence, to fill the gap between what students are acquiring through the curriculum and what it is required, TNSF is planning its activities on higher science to students who are pursuing higher education.
About the Lecture Click chemistry is a term that initially described reactions giving the high yield and selectivity products by carbon-hetero bond formation reactions. The word “click” referred to easily joining molecular building blocks as two pieces of a seat belt buckle. Barry Sharpless coined the concept of click chemistry, where molecular building blocks snap together quickly and efficiently. In 2002, Sharpless and Morten Meldal, independently of each other, developed an elegant and efficient chemical reaction: the copper-catalyzed azide-alkyne cycloaddition. This is now in widespread use and is utilized in the development of pharmaceuticals, for mapping DNA and creating new materials. Around 2000, Carolyn Bertozzi started utilizing click chemistry in living organisms. She developed bioorthogonal reactions which take place inside living organisms without disrupting the normal chemistry of the cell. These reactions are now used to explore cells, track biological processes, and improve the targeting of cancer pharmaceuticals. Barry Sharpless and Morten Meldal are awarded the Nobel Prize in Chemistry 2022 because they brought chemistry into the era of functionalism and laid the foundations of click chemistry. They share the prize with Carolyn Bertozzi, who took click chemistry to a new dimension and began using it to map cells. Her bioorthogonal reactions are now contributing to more targeted cancer treatments, among many other applications.
Introduction Professor KS.Viswanathan Retired Professor, IISER Mohali, Visiting Professor Krea University
Ramray Bhat
Associate Professor, IISc, Bangalore
Click Chemistry
Q & A
Ramray Bhat is an associate professor in the department of Molecular Reproduction, Development and Genetics (MRDG), an associate faculty of the Centre for BioSystems Science and Engineering (BSSE), and a coordinator for undergraduate education in biology at the Indian Institute of Science, Bangalore, India. He has a Bachelor’s degree in medicine (MBBS) from the University of Calcutta, a Ph.D. in developmental biology from the New York Medical College, and was a Komen postdoctoral fellow at the Lawrence Berkeley National Laboratory. His interests lie at the interface of development, evolution, and cancer. He is also a fellow of the Wellcome Trust-DBT India Alliance and the EMBO Global Investigator Network.
Prof. K. S. Viswanathan, is Visiting Professor, Division of Sciences, Krea University, India. He obtained his Ph. D. in Physical Chemistry from Vanderbilt University, USA. He held various positions during his academic and research life. He served as Professor, Dept. Chemical Sciences, IISER Mohali (Aug 2011-Sept 2018) & Visiting Professor (Oct 2018-May 2019), Adjunct Faculty, Department of Chemistry, Indian Institute of Technology Madras, Chennai 600 036 (May 2020-May 2022), Head of the Department of Chemical Sciences, IISER Mohali (Aug 2012-Sept 2017), Dean (Students) at IISER, Mohali (Jan 2014-Jan 2016), Professor in Homi Bhabha National Institute, (Deemed Univ), IGCAR, Kalpakkam (May 2006-July 2011), Dean (Academic), Homi Bhabha National Institute, (Deemed Univ), IGCAR, Kalpakkam (May 2006-July 2010) and Head, Analytical Chemistry & Spectroscopy Section, Materials Chemistry Division, IGCAR, Kalpakkam (Mar 2004-July 2011). His Research Interests are in Matrix isolation IR spectroscopy for the study of conformations, non-covalent interactions, reactions of high temperature species. Fluorescence spectroscopy of lanthanides and actinides. Laser induced breakdown spectroscopy, Glow Discharge Spectroscopy and Spectroanalytical methods. He is also interested in matters relating to Science Education in schools and universities.