Popular Science Lecture - 57

Gene Editing-based Novel therapeutics


Venue: Auditorium, Taramani Campus
University of Madras,
Chennai

January 08, 2023
4:00 pm - 06:00 pm

Organised by TNSF & UoM

About Program







This is part of its efforts to popularize science to the general public and students who are pursuing science as their career. TNSF attempt to focus on students on higher science as everyone knows that learning of science at college within the curriculum is not enough to acquire holistic knowledge of science at the appropriate time. Hence, to fill the gap between what students are acquiring through the curriculum and what it is required, TNSF is planning its activities on higher science to students who are pursuing higher education.



About the Lecture
For the first time, a new gene editing technology called base editing was used to modify immune cells and successfully treat a teen with treatment-resistant leukemia. A month afterward, 13-year-old Alyssa was in remission, and she continues to do well several months later.

The treatment is a modification of chimeric antigen receptor, or CAR, T-cell therapy. But instead of using the CRISPR gene editing technique to modify the patient’s immune cells, the clinicians used the more precise base editing technique to alter donor immune cells.

மரபணுச் சிகிச்சை என்பது, குறிப்பிட்ட சில நோய்களுக்கான சிகிச்சையாக ஒரு மரபணுவின் வெளிப்பாட்டை மாற்றியமைத்தல் அல்லது சிகிச்சைப் பயன்பாட்டிற்காக உயிரணுக்களின் உயிரியல் பண்புகளை மாற்றியமைத்தல் என்பவற்றை உள்ளடக்கிய ஒரு மருத்துவத் துறையாகும்.

SCHEDULE

Time: 4:00 pm to 6:00 pm - January 08, 2023

Attendenace Registration starts at 3:30 pm

4:00 pm

Introduction

4:10 pm

Dr. Priya Ramanathan
Assistant Professor, The Cancer Institute (WIA), Adyar, Chennai

Lymphoblastic Leukemia

4:55 pm

Dr. Indumathi Mariappan
Research Scientist, Hyderabad Research Foundation, LVPEI,
Member, Task Force on Stem Cell Research & Regenerative Medicine

Possibilities of correcting Genetic Defects

5:35 pm

Dr. V. Aravindhan
Associate Professor, Department of Genetics, University of Madras

Brainstorming Session on Gene Therapy

06:05 pm

Conclusion

Speakers

Dr. Priya Ramanathan,

Dr. Priya Ramanathan

Dr. Priya Ramanathan, is Associate Professor, Cancer Institute(WIA) Adyar, Chennai. Dr. Priya Ramanathan has been working in the field of cancer Immunotherapy for the past 15 years. She had the opportunity to develop the first dendritic cell vaccine therapy program in the country for cervical cancer patients and test the same in a phase I trial. The same has now been extended to phase II. She is currently working on the same along with a dendritic cell vaccine programme using a recombinant SPAG9 protein which was discovered as tumor associated protein. Have published a no. of papers relating to cancer immunotherapy in general and dendritic cell vaccines in particular as well as immune suppression in cancer. Exploring immunotherapeutic options for other cancers is of special interest as well.

Dr. Indumathi Mariappan,

Dr. Indumathi Mariappan

Dr. Indumathi Mariappan, completed her doctoral training in the area of Cell Biology and Molecular Biology at the Centre for Cellular and Molecular Biology (CCMB), Hyderabad in the year 2005. She also underwent a three year post-doctoral training at CCMB before joining the Stem Cell Biology Laboratory at LVPEI in 2008. Dr Mariappan's lab is involved in basic and translational research towards addressing the problems of retinal and corneal diseases using different sources of adult and pluripotent stem cells. Her group is currently exploring the basic biology of limbal stem cells and the applications of embryonic stem cells (hESCs) and patient-specific induced pluripotent stem cells (hiPSCs) in disease modeling and regenerative medicine.

Dr. V. Aravindhan,

Dr. V. Aravindhan

Dr. V. Aravindhan, an Assitant Professor in the Department of Genetics at Madras University did his Ph.D. in Molecular Biology and Vaccine Research. He moved to the USA for his Post-doctoral research work and joined with Food and Drug Administration. He later moved to National Cancer Institute at Fredrick in the USA. He moved back to India and take up the Scientist position in Dept of Transcriptomics and Molecular Immunology, at Madras Diabetes Research Foundation. He later joined Anna University as a Scientist, Laboratory of Molecular Immunology, Life Sciences, AU-KBC, Anna University, MIT campus before taking up a teaching position at Madras University. He has published more than 35 papers.

Venue

Dr. A. Venugopal Auditorium
Taramani Campus, University of Madras
Chennai - 600113

Call

+91 9176512565

Email us

tamilnadutnsfchennai@gmail.com

Past Events

Nobel Prize 2018 - [Physics] and Special Report on Global Warming of 1.5ºC by IPCC
Talk on Raman Effect & Emergence
Talk on Climate Change
LHC and Detection of Higgs Boson
Evolution And Datura - பரிணாம வளர்ச்சியும் ஊமத்தையும்
Science for Peace
Data Science, Artificial Intelligence and Cryptography
Biodiversity in Western Ghats
Nobel Prize 2019 - Physiology and Medicine
Nobel Prize 2019 - Physics
Nobel Prize 2019 - Chemistry
Evidence from a neuroimaging study of Sports
The cryosphere and climate of the earth
Demystifying Coronavirus
The discovery of Hepatitis C virus
The black hole formation and the centre of our galaxy
Genome Editing
From “you and your brain” to “you vs. your brain”
Status of COVID-19 Vaccines
Art and Metal Technology of Chola Bronzes
Himalayan Glaciers - Science & Facts
Covid-19: Created or evolved?
செயற்கை நுண்ணறிவு: வாய்ப்புகளும், சவால்களும்
Next-Generation DNA Sequencing Technologies
Dark Matter and its Detection
Steven Weinberg: The physicist and his physics
The Nobel Prize in Physics 2021
The Nobel Prize in Physiology or Medicine 2021
The Nobel Prize in Chemistry 2021
Science, Equity, and Climate Action at COP-26
A-Satyameva Jayate in Post-Truth India
Unraveling the universe with James Webb Space Telescope
Invisible Empire: How viruses and microbes shape our world
COULD WE BUILD A MINIATURE SUN ON EARTH?
The Story of our Star, the Sun
To be or knot to be
Evolution of Parental Care in frogs and toads
Quantum Entanglement
Genome Sequencing of the Extinct
The Nobel Prize in Chemistry 2022 - Click Chemistry
The 36 officers of Euler: From puzzle to quantum physics
Chemistry through Experiments