This is part of its efforts to popularize science to the general public and students who are pursuing science as their career. TNSF attempt to focus on students on higher science as everyone knows that learning of science at college within the curriculum is not enough to acquire holistic knowledge of science at the appropriate time. Hence, to fill the gap between what students are acquiring through the curriculum and what it is required, TNSF is planning its activities on higher science to students who are pursuing higher education.
How mathematicians think about symmetry Group theory is a way of formalizing symmetry in mathematical language. Mathematicians study the symmetries of flowers, snowflakes, molecules, crystals, and even algebraic and differential equations. We will see how objects can be better understood using their symmetries.
Can a tennis ball penetrate through a brick wall: The story of macroscopic quantum tunneling Tunneling of microscopic systems (e.g., electron, photon, etc.) through energy barrier – higher than the energy of the systems – is a well-known phenomenon in Quantum Mechanics, the physical description of the microscopic world. In classical world, the world where we live in, we don’t get to see such a phenomenon. So, we don’t expect a macroscopic object like a tennis ball to penetrate/tunnel through a solid barrier like a brick wall: the energy of the ball is quite low to overcome the required penetration energy of the wall. The main obstacle to observe tunneling of macroscopic quantum objects is the noise effect on the object by its surroundings, due to which, the possibility of tunneling can become insignificant. In their pathbreaking experiments – done during mid-eighties – John Clarke, Michel H. Devoret, and John M. Martinis (all working at the University of California, Berkeley at that time), managed to overcome this issue of environmental noise effect and showed tunneling of a bulk of superconducting electrons through an energy barrier. These works led to the Nobel Prize in Physics for the year 2025, won by these three physicists. Such a macroscopic quantum phenomenon has led to several important discoveries, including quantum computers with superconducting qubits. In my talk, I will try to provide a brief outline the idea of macroscopic quantum tunneling.
Joy of Discovery in the Modern Era : Some Reflections and Directions In this talk, we shall discuss the project of knowledge production as a profession and as a career, and the calling of a professional. We will present general arguments by looking into some contemporary examples drawn from different disciplines. We will described at a popular level recent discoveries such as gravitational waves which unites physics at the largest and smallest scales and the discovery of the Higgs boson which required a heroic man made machine. We will appeal to other examples from mathematics, computer science, biology, climate science, to name a few to motivate the challenges of the present era. We will also look into the issues of the psychology of creativity. Of importance are also questions of science and engineering in India as a developing country and that of representation of women among others. We will also touch on important issues of the role of the individual, of working in teams, and of communication. Stated differently this talk aims to provide a motivational framework and spells out the gestalt needed for a young person to enter the daunting field of research and discovery and to be a part of the great discoveries that lie ahead. The talk is aimed at a very broad audience and is accessible even to class XI and XII students, and for students across all B. Sc., B. Tech, M.Sc, Ph.D. students in all branches of sciences, and also to teachers and researchers in all areas of science. The speaker is well suited for this as someone with experience in both engineering and science. We wish to leave a lot of time for discussion at the end of the talk and encourage participation from all, young and not so young.
India’s Hidden Frontier: How Indigenous Immunotherapy is Redefining the Fight Against Cancer Could personalized, indigenous gene or cell-based therapies soon turn terminal or fatal diseases into a manageable chronic condition rather than a terminal one? Looking forward into the future, the integration of cutting-edge molecular tools with local research will become the cornerstone of medical independence. However, high powered technological tools may often lack the "warm" human-centric logic required to navigate biological complexity. As we begin to bridge the digital and the biological divide, a defined shift from "technology-oriented" to "individual-oriented" has emerged. Will care become "ubiquitous" in this era— integrating itself into the home, the workplace, and personality of an individual patient?
Introduction
Amritanshu Prasad
Director, Institute of Mathematical Sciences, Chennai
How mathematicians think about symmetry
SIBASISH GHOSH
Optics & Quantum Information Group, The Institute of Mathematical Sciences
Can a tennis ball penetrate through a brick wall:
The story of macroscopic quantum tunneling
Prof. B. Ananthanarayan
Professor and former Chair, Center for High Energy Physics,
Indian Institute of Science Bangalore
Joy of Discovery in the Modern Era : Some Reflections and Directions
Dr. Priya Ramanathan
Cancer Institute (WIA), Adyar, Chennai
India’s Hidden Frontier: How Indigenous Immunotherapy is Redefining the Fight Against Cancer
Q & A
Amritanshu Prasad is a Professor in the Mathematics unit at The Institute of Mathematical Sciences (IMSc) in Chennai, India. His primary research interests are: Combinatorics Representation Theory Harmonic Analysis Automorphic Forms Prof. Prasad has been a faculty member at IMSc since 2003, following a postdoctoral fellowship at the University of Montréal. He is an active educator, having taught a wide range of courses from Algebra and Complex Analysis to Representation Theory, including online courses through NPTEL and IIT Madras. His published work reflects a strong focus on the intersection of combinatorics and representation theory. A notable contribution is his book "Representation Theory: A Combinatorial Viewpoint" (Cambridge University Press, 2015). His recent research, often in collaboration, continues to explore areas such as the representation theory of symmetric groups and combinatorial enumeration over finite fields, with several publications in 2023 and 2024.
Professor Sibasish Ghosh is a senior faculty member at the Theoretical Physics group of The Institute of Mathematical Sciences (IMSc), Chennai. He earned his Ph.D. in 2004 from the Indian Statistical Institute, Kolkata, focusing on entanglement in quantum mechanics. His research spans quantum information theory, quantum optics, entanglement, quantum communication, quantum thermodynamics, and open quantum systems. He is recognized for pioneering work in local distinguishability of quantum states, graph-theoretic connections to quantum information, and quantum heat engines in non-Markovian environments. Prof. Ghosh has supervised 9 Ph.D. graduates, mentors several postdoctoral fellows, and is regarded as one of the early r esearchers to establish quantum information theory as a field in India.
Prof. B. Ananthanarayan is a professor and former chair of the center for High Energy Physics at the Indian Institute of Science. He obtained his B.Tech. in Chemical Engineering from IIT Madras in 1985 (as part of the last five year batch) and completed his M.S. and Ph.D. from the University of Delaware, USA, 1988 and 1991, respectively. After post-doctoral work at the Physical Research Laboratory (PRL) in Ahmedabad, University of Lausanne and Bern, he joined IISc in 1996 and has been there ever since. His research spans several areas of elementary particle physics and field theory. Additionally, he has been involved in editorial work for Springer for over a decade and a half and is well known for his outreach efforts through writings and popular talks. BA was Homi Bhabha Fellow, 2009-2011, was awarded the Rustom Choksi Award for Excellence in Science, 2014 by IISc, held the MSIL Chair of the Division of Physical and Mathematical Sciences, IISc. BA was Chair of CHEP for a record period of over 9 years and 7 months. He is presently on the Governing Council of the IUAC, Delhi, and serves on the India-CERN Task Force of the DAE and DST, and has been recently inducted into the advisory committee for the dual degree of IIIT Hyderabad.
Dr. Priya Ramanathan is a professor and researcher on cancer immunotherapy at Cancer Institute (WIA). In 2013, the journal Science named immunotherapy the "Breakthrough of the Year," signaling a tectonic shift in oncology by leveraging the patient’s own immune system to combat malignancy. While this global recognition validated the field, Dr. Priya Ramanathan, under the guidance and mentorship of Prof T.Rajkumar, a doyen in the field of Molecular Oncology, began the groundwork in the Department of Molecular Oncology since 2003. This early start established the lab as a pioneer in indigenous innovation and placed the Cancer Institute firmly on the Cell therapy trajectory. The lab’s journey began with a project funded by the Department of Biotechnology (DBT) focusing on therapeutic dendritic cell (DC) vaccines for HPV-positive cervical cancer. This landmark research resulted in the first immune cell-based clinical trial ever conducted in India, a pivotal moment for the nation’s healthcare infrastructure. Dr. Ramanathan’s mission is centered on building a self-reliant future for advanced medicine. She notes: "Our current interest is in developing point-of-care cell therapies indigenously, backed by cutting-edge research and state-of-the-art molecular tools." This commitment ensures that cutting-edge cancer treatments are developed within the country, fostering a robust framework for independent biomedical strategy. For cell-based therapies to be effective on a national scale, they must transition from laboratory prototypes to a GMP-compliant manufacturing reality. Dr. Ramanathan’s team achieved a significant breakthrough by shifting from traditional culture plates to surface-coated culture bags for generating clinical-grade mature DCs (mDCs). This common, scaled-up protocol allows for consistent production without compromising the functional or phenotypic quality of the cells. Her current focus is on improving vaccine efficacy by targeting IDO activity specifically during the maturation of the DC vaccine.